Teratogenic Effects of Bisphenol A Exposure During Maternal Pregnancy and Lactation on Developing Rat Pups Testes

Objective: To study the teratogenic effects of Bisphenol A exposure during maternal pregnancy and lactation on testicular histology developing rat pups.
 Design Study: Laboratory-based experimental study.
 Place Duration Department Anatomy, Islamic International Medical College Rawalpindi in collaboration with National Institute Health (NIH) Islamabad Pakistan from Sep 2018 to 2019.
 Methodology: Eight weeks old, ten pregnant female rats were divided into groups, each comprising five rats. Pups born by spontaneous vaginal delivery. Control group consisted 15 male pups delivered 5 rats, fed a standard diet till 21st day. Experimental B who administered subcutaneous at dose their day.
 Results: Significant deterioration quantitative parameters testes was seen. The seminiferous tubule diameter 81.99 ± 10.88 compared which 111.59 8.36. germinal epithelial height 10.47 2.34 30.41 2.43 A. number Leydig cells 17 3.45 47 4.44 rounded spermatids 10 3.74 38 4.02 A.
 Conclusion: has rats............